Key Findings Summary of the Time Restricted Diet
- Research confirms that the 16:8 time restricted diet combined with resistance training does not result in muscle loss.
- Participants following a 16:8 protocol saw significant reductions in body fat and overall body mass.
- Improved insulin sensitivity and reductions in LDL cholesterol levels were observed with a time-restricted diet, contributing to better overall health.
Introduction to a Time Restricted Diet
For years, bodybuilders have adhered to the long-standing advice of eating six meals a day to optimize muscle growth. However, a new trend in fitness—time-restricted eating—has sparked debate. While many feared that fasting periods would lead to muscle loss, the study “Synergistic Effects of Time-Restricted Feeding and Resistance Training on Body Composition and Metabolic Health “1, reveals otherwise. Published in Nutrients, this study demonstrates that a 16:8 time restricted diet, when paired with resistance training (RT), can effectively reduce fat while preserving muscle mass.
What is the 16:8 Protocol?
The 16:8 time-restricted diet is a popular intermittent fasting strategy where individuals fast for 16 hours and consume all their daily calories within an 8-hour eating window. For instance:
- A typical schedule might involve eating between 12:00 PM and 8:00 PM, followed by fasting until the next day.
- During the fasting period, only water, black coffee, or herbal teas are allowed, ensuring no caloric intake.
This approach simplifies meal planning and focuses on when you eat rather than what you eat, making it both practical and sustainable for many people. The 16:8 protocol aligns well with modern lifestyles, allowing flexibility. It’s particularly appealing for individuals who skip breakfast or prefer to consume their calories later in the day.
Overview of the Study Protocol
This systematic review and meta-analysis synthesized data from seven trials involving 164 participants. Participants were divided into two groups: those following the 16:8 time restricted feeding (TRF) protocol with RT and those adhering to a conventional diet paired with RT.
Diet Restricted Diet Protocol Highlights:
This systematic review and meta-analysis synthesized data from seven trials involving 164 participants. Participants were divided into two groups: those following the 16:8 time restricted diet (TRF) protocol with RT and those adhering to a conventional diet paired with RT.
TRF group: An 8-hour eating window (e.g., 12:00 PM–8:00 PM), with fasting for the remaining 16 hours.
Control group: Habitual meal patterns without specific time restrictions.
Resistance Training Regimen: Exercises included standard weightlifting movements targeting multiple muscle groups (e.g., bench press, leg press).
Intensity: 6–12 repetitions at 70–90% of one-rep max (1RM), performed 3–4 times per week.
Duration: Study durations ranged from 4 weeks to 12 months, with most interventions lasting 8 weeks.
Does a Time Restricted Diet Result in Muscle Mass Loss?

Muscle Mass and Strength: Contrary to common concerns, the time restricted diet or TRF group maintained muscle mass and strength levels comparable to the control group. Notably, both groups saw improvements in their one-rep max for key exercises like the bench press and leg press. This finding disproves the myth that a diet restricted diet leads to muscle loss.
Fat Loss: Participants following the 16:8 TRF protocol experienced greater reductions in body fat (average loss of 1.52 kg [3.35 lbs] and body weight (average loss of 2.90 kg [6.39 lbs] compared to the control group. The TRF group also showed reduced visceral fat, a crucial marker for metabolic health.
Metabolic Health: Significant improvements were observed in insulin sensitivity and lipid profiles. TRF participants experienced reductions in:
- Insulin levels (SMD −0.72)
- LDL cholesterol (−9.94 mg/dL)
- Total cholesterol (−9.44 mg/dL)
Dispelling the Myth that a Diet Restricted Diet Will Result in Muscle Loss

One of the primary advantages of the time restricted diet is its ability to facilitate weight loss and improve metabolic health. Studies indicate that time restricted diet can lead to significant reductions in body weight and fat mass, particularly in individuals with obesity or metabolic disorders.2 For instance, a systematic review highlighted that TRE resulted in a notable decrease in body fat without significantly affecting lean body mass in various populations, including older adults.3 This is crucial, as preserving muscle mass during weight loss is essential for maintaining metabolic rate and overall health.
Time Restricted Diet and Resistance Exercise
In terms of muscle mass, preserving lean tissue during weight loss is critical. Research indicates that TRE can support muscle maintenance when combined with adequate protein intake and resistance training.4 However, the timing of protein consumption is also crucial; spreading protein intake evenly throughout the day may enhance muscle protein synthesis, which is vital for muscle preservation during caloric restriction.5 Therefore, individuals practicing TRE should prioritize high-quality protein sources during their eating windows to support muscle health.
Practical Applications for Using a Time Restricted Diet
- Choose Your Eating Window: Opt for a window of the time restricted diet that aligns with your lifestyle. For instance, eating from 12:00 PM to 8:00 PM allows for a flexible lunch and dinner schedule.
- Pair with Effective Resistance Training: Follow a well-rounded routine targeting major muscle groups. Aim for 3–4 sessions per week, using compound exercises like squats and deadlifts.
- Prioritize Protein Intake: Ensure you consume at least 1.6 grams of protein per kilogram of body weight during your eating window to support muscle repair and growth.
- Monitor Progress: Track changes in your body composition and strength to assess the effectiveness of your plan.
References
1 Ho, Y., Hou, X., Sun, F., Wong, S. H. S. & Zhang, X. Synergistic Effects of Time-Restricted Feeding and Resistance Training on Body Composition and Metabolic Health: A Systematic Review and Meta-Analysis. Nutrients 16 (2024). https://doi.org/10.3390/nu16183066
2 Jamshed, H. et al. Effectiveness of Early Time-Restricted Eating for Weight Loss, Fat Loss, and Cardiometabolic Health in Adults With Obesity. Jama Internal Medicine 182, 953 (2022). https://doi.org/10.1001/jamainternmed.2022.3050
3 Anton, S. D. et al. The Effects of Time Restricted Feeding on Overweight, Older Adults: A Pilot Study. Nutrients 11, 1500 (2019). https://doi.org/10.3390/nu11071500
4 Tinsley, G. M. & Paoli, A. Time-Restricted Eating and Age-Related Muscle Loss. Aging 11, 8741-8742 (2019). https://doi.org/10.18632/aging.102384
5 Aragon, A. A. & Schöenfeld, B. J. Does Timing Matter? A Narrative Review of Intermittent Fasting Variants and Their Effects on Bodyweight and Body Composition. Nutrients 14, 5022 (2022). https://doi.org/10.3390/nu14235022